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Frequently Asked Questions

All your questions about head pain, head health, Excedrin, products answered.

Usage and Safety

PREGNANCY & BREASTFEEDING

SAFETY

  • I have heard that caffeine may not be safe. Is that true?

    Caffeine has been an ingredient in both OTC and prescription drug products for many decades. Medical research has demonstrated that caffeine is a safe and effective addition to the combination of acetaminophen and aspirin in medications for relief of pain when used at the appropriate dose. The acetaminophen-aspirin-caffeine combination is approved and clinically proven to be effective and well-tolerated for the relief of both migraine and tension-type headache pain, but as always, you should follow package directions.

    The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heartbeat.

    Learn more about caffeine

  • Can you give kids Excedrin Migraine?

    Excedrin Migraine is not recommended for people under age 18.

    View the full Ingredient and Dosing Chart.

  • Is it safe to take products containing acetaminophen?

    The FDA has determined that acetaminophen is safe for most people to use, when taken as directed. Take acetaminophen and all other medications according to the package directions. For further information or to discuss personal health concerns, please consult your pharmacist or physician.

  • What can I take with Excedrin?

    You should ask a doctor or pharmacist before taking Excedrin products if you are taking any other drug.

  • Can you take Excedrin with alcohol?

    Excedrin products contain acetaminophen. Severe liver damage may occur if you consume 3 or more alcoholic drinks every day while using these products. Most Excedrin products also contain aspirin, an NSAID, which may cause severe stomach bleeding. The chance is higher if you have 3 or more alcoholic drinks every day while using these products.

  • I’m already taking another drug for migraine; can I take Excedrin Migraine too?

    If you are taking a prescription medication, please consult your doctor before combining it with any over-the-counter medication, including Excedrin Migraine.

DOSAGE

  • How many Excedrin can I take in a day?

    Adults and children 12 years of age and older should follow the below dosage guidelines:

    Excedrin Extra Strength – Do not use more than directed. Drink a full glass of water with each dose. Adults and children 12 years and over: take 2 caplets every 6 hours; not more than 8 caplets in 24 hours. Children under 12 years: ask a doctor.

    Excedrin Tension Headache – Do not use more than directed. Adults and children 12 years and over: take 2 caplets every 6 hours; not more than 6 caplets in 24 hours. Children under 12 years: ask a doctor.

    Adults age 18 or older should follow the below dosage guidelines when taking Excedrin Migraine:

    Excedrin Migraine – Do not use more than directed. Adults: take 2 caplets with a glass of water. If symptoms persist or worsen, ask your doctor. Do not take more than 2 caplets in 24 hours, unless directed by a doctor. Under 18 years of age: ask a doctor.

    View the full Ingredient and Dosing Chart.

SIDE EFFECTS

More from Excedrin

Head Care products are not intended to treat migraines.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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